Kinetic and Mechanistic Study of Bromination of Benzofuran Scaffolds

by Venkat, Suryawanshi
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Venkat, Suryawanshi Kinetic and Mechanistic Study of Bromination of Benzofuran Scaffolds
Venkat, Suryawanshi - Kinetic and Mechanistic Study of Bromination of Benzofuran Scaffolds

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It is difficult to imagine the synthesis without organobromides. It has been widely used as reactive intermediates and as a versatile synthons in various organic syntheses. a-Bromination of carbonyl compound is an important reaction in organic synthesis; as the resulting a-bromo-ketones are used in the synthesis of variety of bioactive molecules. Clinically, physiologically important and widely used benzofuran derivatives can be obtained from a-bromo carbonyl compounds. In recent past, organic Quaternary Ammonium tribromide (QATBs) have been reported to be crystalline, highly efficient, selective, easy to transport, handling and storage; maintain the desired stoichiometry and Ecofriendly protocol for Bromination. Considering the importance of a -bromo synthetic derivatives of benzofuran moiety and Quaternary Ammonium tribromide (QATBs) we have used efficient and environmentally benign protocol phenyl trimethyl ammonium tribromide (PTT) for a-Bromination of various benzofuran scaffolds. In view of this systematic kinetics and mechanistic aspects for the Bromination of benzofuran compounds and the synthesis of various bromoacetyl benzofuran scaffold have been described in this book.


Venkat, Suryawanshi
Appasaheb, Suryavanshi

Further information

Biography Artist:
Dr. Suryawanshi Venkat Shivaji is an associate professor at Dept.of Chemistry, Shri Chhatrapati Shivaji College, Omerga,Osmanabad District in Maharashtra India. He obtained M.Sc. in Chemistry followed by PhD from Dr. Babasaheb Ambedkar Marathwada University, Aurangabad. He has 20 years teaching experience and published a number of research papers.
Number of Pages:
Media Type:
LAP Lambert Academic Publishing

Master Data

Product Type:
Paperback book
Release date:
March 30, 2020
Package Dimensions:
0.22 x 0.15 x 0.009 m; 0.286 kg
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