MRI and Nanoparticle Tracking of Stem Cells

by Lee, Eddy
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Lee, Eddy MRI and Nanoparticle Tracking of Stem Cells
Lee, Eddy - MRI and Nanoparticle Tracking of Stem Cells

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Description

Stem cell therapy is an emerging field of regenerative medicine that has the potential to treat diseases by transplanting therapeutic cells to replace or support the repair of damaged host cells. An important step of the therapeutic success is the homing of transplanted cells to the desired site. Magnetic resonance imaging (MRI), coupled with cellular markers, offers a non-invasive method of following the fate of cell transplants during the therapeutic period. However, clinically and commercially available markers do not offer sufficient image contrast for the detection of small groups of cells. The aim of this thesis is to investigate the development of particulate cellular markers that will improve the tracking of stem cells in an animal model through MRI. Current markers for cellular labelling are composite, magnetic particles that measure less than 100 nm or greater than 1 micron in diameter. As the intermediate range has not been investigated, microgel iron oxide particles (MGIO) with the diameters of 89 to 765nm were synthesised and characterised in terms of their physical properties.

Contributors

Author:
Lee, Eddy

Further information

Biography Artist:
Lee, Eddy
Eddy Lee is interested in multi-disciplinary medical imaging research. Currently, he runs a venture capital fund focused on early stage startups. He mentors at Stanford University's StartX accelerator among other institutions, and was previously a Consulting Professor at Stanford, and a circuit design engineer.
Language:
English
Number of Pages:
288
Media Type:
Softcover
Publisher:
LAP Lambert Academic Publishing

Master Data

Product Type:
Paperback book
Release date:
July 19, 2019
Package Dimensions:
0.22 x 0.15 x 0.017 m; 0.476 kg
GTIN:
09786139925254
DUIN:
MC4UP6END39
$92.99
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