Protein Scaffolds - Design, Synthesis, and Applications

by Springer US
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Springer US Protein Scaffolds - Design, Synthesis, and Applications
Springer US - Protein Scaffolds - Design, Synthesis, and Applications

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Description

This volume provides a wide range of methods and protocols detailing various protein structures as platforms for building architectures with targeted application. Chapters guide the readers through exploiting a number of protein scaffolds including virus nanoparticles, elastin and collagen peptides and proteins, and other protein templates for either building materials or presentation of ligands. Site-specific bioconjugation methods, some unique protein architectures, and techniques that exploit peptide amphiphile micelles and assembly of chaperones are also featured. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 


Authoritative and cutting-edge, Protein Scaffolds: Design, Synthesis, and Applications aims to ensure successful results in the study of this vital field.


Further information

Illustrations Note:
24 SW-Abb., 52 Farbabb.
Table of Contents:

1. Nanoreactors via Encapsulation of Catalytic Gold Nanoparticles within Cowpea Chlorotic Mottle Virus



Aijie Liu, Mark V. de Ruiter, Stan J. Maassen, and Jeroen J.L.M. Cornelissen



 



2. Encapsulation of Active Enzymes within Bacteriophage P22 virus-like Particles



Dustin P. Patterson



 



3. Encapsulation of Exogenous Proteins in Vault Nanoparticles



Meng Wang, Danny Abad, Valerie A. Kickhoefer, Leonard H. Rome, and Shaily Mahendra



 



4. Enzyme Encapsulation in an Engineered Lumazine Synthase Protein Cage



Yusuke Azuma and Donald Hilvert



 



5. Metal Ion-induced Self-Assembly and Packaging of CCMV Nanocapsules



Lise Schoonen, Mark B. van Eldijk, and Jan C. M. van Hest



 



6. Modification of CCMV Nanocages for Enzyme Encapsulation



Lise Schoonen and Jan C. M. van Hest



 



7. Synthesis of Cross-linked 2-aminoethyl Methacrylate in P22 Viral Capsid via Atom-transfer Radical Polymerization



Shefah Qazi   



 



8. Synthesis of Metal-organic Frameworks on Tobacco Mosaic Virus Templates



Shaobo Li and Jeremiah J. Gassensmith



 



9. TMV Disk Scaffolds for Making sub-30 nm Silver Nanorings



Serene Bayram, Omar Zahr, Julia Del Re, and Amy Szuchmacher Blum



 



10. TMV Disk Scaffolds for Making sub-30 nm Silver Nanorings



Serene Bayram, Omar Zahr, Julia Del Re, and Amy Szuchmacher Blum



 



11. Synthesis of Triangular Silver and Gold Nanoprisms Using Consensus Sequence Tetratricopeptide Repeat Proteins



Xi Geng  and Tijana Z. Grove



 



12. Type III Secretion Filaments as Templates for Metallic Nanostructure Synthesis



Anum Azam Glasgow



 



13. Incorporation of Non-canonical Amino Acids into Proteins by Global Reassignment of Sense Codons



Katharine Y. Fang, Seth A. Lieblich, and David A. Tirrell



 



14. Modification of Protein Scaffolds via Copper-catalyzed Azide‚ÄďAlkyne Cycloaddition



Stanislav Presolski



 



15. Antibody Modification of p-aminophenylalanine-containing Proteins



Adel M. ElSohly, Chawita Netirojjanakul, and Matthew B. Francis



 



16. Cross-linked Collagen Gels using Gold Nanoparticles



Katarzyna Slowinska



 



17. Genipin Cross-linking Of Elastin and Elastin-based Proteins



Lisa D. Muiznieks



 



18. Characterization of Self-Assembled Protein Scaffolds from Collagen-mimetic Peptides



Devyani Shukla, Jayeeta Lahiri, and Avanish Singh Parmar



  19. Design and Characterization of Fibers and Bionanocomposites Using the Coiled-coil Domain of Cartilage Oligomeric Matrix Protein

Priya Katyal and Jin Kim Montclare



 



20. Preparing Genes for Repetitive Elastin-like Polypeptides Using Gibson Assembly



James K. Deyling, Edward M. Turk, and Nolan B. Holland



 



21. Peptide Amphiphile Micelles for Vaccine Delivery



John C. Barrett and Matthew V. Tirrell



 



22. Controlled Assembly of the Filamentous Chaperone Gamma-prefoldin into Defined Nanostructures



Douglas S. Clark and Dominic J. Glover



 



23. Advances in the Application of Designed Ankyrin Repeat Proteins (Darpins) As Research Tools and Protein Therapeutics



Ykelien L. Boersma



 

Editor:
Udit, Andrew K.;Udit
Remarks:
Includes cutting-edge methods and protocols


Provides step-by-step detail essential for reproducible results


Contains key notes and implementation advice from the experts

Media Type:
Hardcover
Publisher:
Springer US
Language:
English
Edition:
1st ed. 2018
Number of Pages:
330

Master Data

Product Type:
Hardback book
Release date:
June 5, 2018
Package Dimensions:
0.254 x 0.178 x 0.021 m; 0.822 kg
GTIN:
09781493978922
DUIN:
K6HTEKP6DFO
$188.64
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