Modeling of Bio-Activity and Toxicity in Light of NA Bases Interaction

by Mondal Roy, Sutapa
State: New
$49.99
VAT included - FREE Shipping
Mondal Roy, Sutapa Modeling of Bio-Activity and Toxicity in Light of NA Bases Interaction
Mondal Roy, Sutapa - Modeling of Bio-Activity and Toxicity in Light of NA Bases Interaction

Do you like this product? Spread the word!

$49.99 incl. VAT
Only 1 items available Only 1 items available
Delivery: between Tuesday, October 5, 2021 and Thursday, October 7, 2021
Sales & Shipping: Dodax

Check other buying options

1 Offer for $49.99

Sold by Dodax EU

$49.99 incl. VAT
State: New
Free Shipping
Delivery: between Tuesday, October 5, 2021 and Thursday, October 7, 2021
View other buying options

Description


Biological activity and toxicity of molecules are the major aspects on understanding diverse bio-mechanisms in living systems. Estimation of degree of activity and toxicity of molecules in a target is very important for their control and applications. However, experimental determination of bio-activity or toxicity is a mammoth task due to cost, time and availability of resources. In this direction, a fruitful mathematical approach has been successfully developed as Quantitative Structure Activity Relationship (QSAR). A successful QSAR modeling can also predict the bio-activity and toxicity of unknown homologous compounds. The present book addresses details of QSAR methods and relevant statistical analysis, various structural descriptors along with a couple of case studies considering important role of nucleic acid bases during the interaction of bio-active/toxic molecules with biological targets. The bio-activity of a series of acyl-CoA: cholesterol O-acyltransferase (ACAT) inhibitors, viz. aminosulfonyl ureas and toxicity of a series of Polycyclic Aromatic Hydrocarbons (PAHs) are reported in light of their interaction with model bio-systems.

Contributors

Author:
Mondal Roy, Sutapa
Roy, Debesh R.

Further information

Biography Artist:
Mondal Roy, Sutapa
Dr. Mondal Roy is an Asst. Prof. of Chemistry at Uka-Tarsadia Univ, Bardoli, India and obtained Ph.D. from Jadavpur Univ, Kolkata. Over 20 of her publications are cited with h-index 8. Dr. Roy is an Asso. Prof. of Physics at S.V. NIT, Surat, India and obtained Ph.D. from IIT Kharagpur, India. Over 100 of his publications are cited with h-index 23.
Language:
English
Number of Pages:
68
Media Type:
Softcover
Publisher:
Scholar's Press

Master Data

Product Type:
Textbook
Release date:
August 21, 2019
Package Dimensions:
0.22 x 0.15 x 0.004 m; 0.15 kg
GTIN:
09786138910275
DUIN:
KHVPLD5EU11
$49.99
We use cookies on our website to make our services more efficient and more user-friendly. Therefore please select "Accept cookies"! Please read our Privacy Policy for further information.