Genetic and Environmental Risk Factors Associated with Type 2 Diabetes

by Ahmed, Feroza
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Ahmed, Feroza Genetic and Environmental Risk Factors Associated with Type 2 Diabetes
Ahmed, Feroza - Genetic and Environmental Risk Factors Associated with Type 2 Diabetes

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Description

Diabetes mellitus (DM) is a heterogeneous disorder resulting from an interaction of numerous genetic and environmental factors. It is a disease that has strong clustering in families and has genetic component. Current study was aimed to determine familial clustering, inheritance pattern and the influence of consanguineous marriages on the aggregation of type 2 diabetes mellitus in a sample population of Balouch community. Study was further extended towards the estimation of antioxidant enzyme activities and lipid peroxidation in diabetic subjects in Balouch and Punjabi community. Lipid peroxidation product of thiobarbituric acid compound (malondialdehyde MDA) was used as indicator of membrane damage while levels of antioxidant enzymes were considered as markers for vascular injury. In conclusion, Family history index was found to be a useful parameter used to measure the risk for developing type 2 DM. Consanguinity plays an important role in the aggregation of type 2 DM in families having diabetic subjects. Offsprings and siblings of type 2 DM patients have a greater risk to developing diabetes at any time during their life span.

Contributors

Author:
Ahmed, Feroza
Naqvi, Farzana

Further information

Biography Artist:
I am Feroza Ahmed Research officer of Dept of Anesthesia Aga khan university. Karachi Pakistan. I have completed my M.Phil (2010)in genetics. I worked to familial clustering, inheritance pattern, influence of consanguineous marriages on the aggregation of type 2 DM in Pakistan.I have got a research article published in New York Accedemic of science
Language:
Englisch
Number of Pages:
196
Media Type:
Buch Broschiert
Publisher:
LAP Lambert Academic Publishing

Master Data

Product Type:
Paperback book
Package Dimensions:
0.22 x 0.15 x 0.011 m; 0.34 kg
GTIN:
09783846520857
DUIN:
C94AV1H845D
Manufacturer Part Number:
34228063
$88.74
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